Sermorelin is a synthetic analog of growth hormone–releasing hormone (GHRH) that corresponds to the biologically active N-terminal fragment of the native human sequence. It is widely studied in endocrinology and molecular biology research for its role in signaling pathways that regulate growth hormone secretion from the anterior pituitary.
In research settings, sermorelin is examined for its effects on growth hormone pulsatility, hypothalamic–pituitary axis signaling, and downstream pathways involving insulin-like growth factor-1 (IGF-1). Unlike exogenous growth hormone, sermorelin is used in experimental models to explore endogenous stimulation mechanisms and feedback regulation within the endocrine system.
Research involving sermorelin centers on hormonal signaling dynamics, receptor-mediated activity, and endocrine regulation rather than therapeutic or clinical application.
