BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide originally identified in human gastric juice. In oral research contexts, it is primarily studied for its role in gastrointestinal signaling, epithelial integrity, and mucosal repair mechanisms.
Laboratory and preclinical studies examining oral exposure focus on BPC-157’s interaction with the gut lining, nitric oxide signaling pathways, angiogenic responses, and inflammatory modulation within the gastrointestinal tract. It has also been explored for its effects on gut–brain signaling, barrier function, and stress-response pathways related to digestive health.
Research involving oral BPC-157 centers on gastrointestinal systems, local tissue signaling, and enteric regulation rather than therapeutic or clinical application.



