Recombinant human growth hormone (rHGH) is a synthetically produced polypeptide that is structurally identical to naturally occurring human growth hormone. It is widely studied in molecular biology and endocrinology research due to its central role in regulating growth hormone signaling through the growth hormone receptor (GHR) and downstream insulin-like growth factor-1 (IGF-1) pathways.
In research settings, rHGH is examined for its effects on protein synthesis, lipid metabolism, glucose regulation, and cellular growth processes. It has also been used extensively in studies exploring tissue regeneration, cell proliferation, and endocrine system feedback mechanisms involving the hypothalamic–pituitary axis.
Research involving rHGH focuses on hormonal signaling cascades, metabolic regulation, and cellular response mechanisms rather than therapeutic or clinical application.
