Melanotan II (MT-2) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) designed to activate melanocortin receptors, particularly MC1R, MC3R, and MC4R. It is widely studied in molecular biology and neuroendocrinology research due to its broad receptor activity across pigmentation, metabolic, and central nervous system pathways.
In research and preclinical settings, MT-2 is examined for its effects on melanogenesis, appetite regulation, energy balance signaling, and central melanocortin pathway modulation. Its ability to engage both peripheral and central receptors makes it useful for studying how melanocortin signaling influences diverse physiological systems.
Research involving MT-2 focuses on receptor interactions, downstream signaling mechanisms, and neuroendocrine regulation rather than therapeutic or clinical application.


